Born in Lisbon, Varela joined local S.L. Benfica's youth system at the age of 11. On 22 September 2012, whilst still a junior, he made his professional debut, appearing forthe reserves in a 2–0 away win against C.D. Aves for the Segunda Ligachampionship.
On 2 July 2016, Varela left Benfica and signed with fellow Primeira Liga side Vitória F.C. until June 2021
|ull name||Bruno Miguel Semedo Varela|
|Date of birth||4 November 1994|
|Place of birth||Lisbon, Portugal|
|Height||1.91 m (6 ft 3 in)|
|2015–2016||→ Valladolid (loan)||1||(0)|
* Senior club appearances and goals counted for the domestic league only and correct as of 15 May 2016.